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Patient Case Studies

Urgent warfarin reversal in action

Explore key KCENTRA uses in a range of patient types through hypothetical case studies.

Choose KCENTRA for patients with acute major bleeding

Intracranial hemorrhage case

Hemorrhage case

Medical history

  • • Atrial fibrillation
  • • Diabetes mellitus
  • • Chronic kidney disease (renal failure)
  • • Congestive heart failure (CHF)
  • • Hypertension Risk of hematoma expansion

Current medications include warfarin 7.5 mg once daily, hydralazine, insulin, atorvastatin, and lisinopril.

Choose KCENTRA for urgent or emergent cardiac surgery

Emergent Cardiac Surgery Case

Emergent Cardiac case

Medical history

  • • Coronary artery disease (CAD) without myocardial infarct
  • • Paroxysmal atrial fibrillation
  • • Peripheral vascular disease
  • • Hypertension
  • • Osteoarthritis

Current medications include warfarin 4 mg once daily, aspirin 81 mg once daily, diltiazem extended-release 120 mg daily, atorvastatin 80 mg daily, and losartan 50 mg daily.

Choose KCENTRA for patients requiring urgent surgery due to an orthopedic trauma or fracture

Orthopedic fracture case

Orthopedic fracture case

Medical history

  • • Deep vein thrombosis
  • • COPD
  • • Osteoporosis
  • • Congestive heart failure (CHF)
  • • Chronic kidney disease (renal failure) Fluid overload risk

Current medications include warfarin 7.5 mg once daily, LAMA/LABA/ICS, albuterol, enalapril, and furosemide.

COPD, chronic obstructive pulmonary disease; ICS, inhaled corticosteroid; LABA, long-acting beta-agonist; LAMA, long-acting muscarinic antagonist.

Choose KCENTRA for hemodynamically unstable GI bleeds

Gastrointestinal bleeding case

Gastrointestinal bleeding case

Medical history

  • • Aortic valvular disease (AF)
  • • High blood pressure
  • • Chronic kidney disease (renal failure)
  • • Congestive heart failure (CHF) Fluid overload risk

Current medications include warfarin 5 mg once daily, a Beta-Adrenergic Receptor Blocker, and an ACE inhibitor.

KCENTRA is proven to reverse warfarin in patients who need it most

See where to use KCENTRA